Glutamine, the most abundant amino acid in the body's promotes healthy everyday tissue repair. In the gut, it maintains intestinal integrity by supporting the protective mucosal lining and by maintaining healthy villous function. It is also an important metabolic fuel for the enterocytes and immune cells in the small intestine. N-acetyl-dglucosamine is a component of glycosaminoglycans and glycoproteins found in the gut's mucosal surface. Gamma oryzanol has a history of use in gastrointestinal applications, with preclinical data supporting its potential to moderate gastric secretions and promote gut function. The polysaccharide-rich inner filet of aloe vera maintains healthy prostaglandin metabolism, immune mediator activity and antioxidant defenses. In a randomized, double-blind clinical trial, volunteers reported positive intestinal support compared to placebo after 4 weeks of aloe vera supplementation.