Est-Adapt is an estrogen-only formulation, maximizing dosing options. Other brands combine estriol and progesterone in the same formula, negating the opportunity for precision dosing. This creates limitations for addressing clinical needs and eliminates the option to use estrogen on its own. Est-Adapt, containing only bioidentical estrogen, enables personalized dosing of estrogen based on your individual needs.

USP estriol helps support sexual development, balanced menstrual cycles, pregnancy, and healthy menopause. BioMatrix estrogen is derived from an extraction of the steroidal backbone of the Mexican Wild Yam (Dioscorea villosa). It is bioidentical, which means it possesses the same molecular structure as that produced naturally by the body.

Vitamin E (mixed with tocopherols) is a blend of natural-source alpha-tocopherol and mixed tocopherols. BioMatrix Est-Adapt uses premium vitamin E in mixed tocopherol forms for enhanced stability and oxidative protection.

Rice Bran Oil is a reliable oil carrier that contributes to the stability and viscosity of numerous formulas.

What Est-Adapt does:

  • Provides bioidentical estrogen
  • Eases symptoms associated with a deficiency or imbalance of estrogen, such as irregular menstrual cycles, headaches, hot flashes, and vaginal dryness

Nutrition & Ingredients:

Per drop:

0.5mg of Estriol (topical oil)

Other ingredients: Rice Bran Oil‚ USP Estriol, Vitamin E (with mixed tocopherols)



SHAKE WELL, then apply 2 to 8 drops. Repeat procedure twice daily, or as directed by your healthcare practitioner. For optimal use, shake the bottle well then clear the dropper three or four times prior to each use. 

Bottle is 1/3 full by design! This allows for optimal dispersion of the formula when shaking.

Store at room temperature.

Cautions / Contraindications:

Always consult with your healthcare practitioner before use.


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