Pro-Adapt is a progesterone-only formulation, maximizing dosing options. Other brands combine estriol and progesterone in the same formula, negating the opportunity for precision dosing. This creates limitations for addressing clinical needs and eliminates the option to use progesterone on its own. Pro-Adapt, containing only bioidentical progesterone, enables personalized dosing of progesterone based on your individual needs.

USP Progesterone helps support the menstrual cycle, pregnancy, and embryo development. It is produced in the corpus luteum of the ovaries each month after a woman ovulates, and helps prepare for a fertilized egg directly after ovulation by thickening the lining of the uterus. BioMatrix progesterone is derived from an extraction of the steroidal backbone of the Mexican Wild Yam (Dioscorea villosa). It is bioidentical, which means it possesses the same molecular structure as that produced naturally by the body.

Vitamin E (mixed with tocopherols) is a blend of natural-source alpha-tocopherol and mixed tocopherols. An independent assay of a leading brand of oil-based hormones determined that only one form of vitamin E (tocopheryl acetate) is included in their formula. Acetate is cheap acid, used in wood glue. In contrast, BioMatrix Est-Adapt uses premium vitamin E in mixed tocopherol forms for enhanced stability and oxidative protection.

Rice Bran Oil is a reliable oil carrier that contributes to the stability and viscosity of numerous formulas.

What Pro-Adapt does:

  • Provides bioidentical progesterone
  • Eases symptoms associated with a deficiency or imbalance of progesterone, such as irregular or shortened menstrual cycles, anxiety, and PMS

Nutrition & Ingredients:

Per drop (approx. 500 drops per bottle):

4.0mg of Progesterone (topical oil)

Other ingredients: Rice Bran Oil‚ USP Progesterone, Vitamin E (with mixed tocopherols)


SHAKE WELL, then apply 5 to 20 drops. Repeat procedure twice daily, or as directed by your healthcare practitioner. For optimal use, shake the bottle well then clear the dropper three or four times prior to each use. 

Bottle is 1/3 full by design! This allows for optimal dispersion of the formula when shaking.

Store at room temperature.

Cautions / Contraindications:

Always consult with your healthcare practitioner before use.


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